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1) "Interleukin" -- As to interleukin in·ter·leu·kin
Pronunciation: "in-t&r-'lü-k&n
Function: noun
Etymology: inter- + leuk- + 1-in
: any of various cytokines of low molecular weight that are produced by lymphocytes, macrophages, and monocytes and that function especially in regulation of the immune system and especially cell-mediated immunity Pronunciation Symbols
Interleukins are a group of cytokines (secreted signaling molecules) that were first seen to be expressed by white blood cells (leukocytes, hence the -leukin) as a means of communication (inter-). The name is something of a relic though; it has since been found that interleukins are produced by a wide variety of bodily cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. A list of interleukins with function: - IL-1: secreted by macrophages, induces acute phase reaction, fever.
- IL-2: secreted by T cells in an autocrine fashion, stimulates growth and differentiation of T cell response. Can be used in immunotherapy to treat cancer.
- IL-3: secreted by T cells, stimulates bone marrow stem cells.
- IL-4: involved in proliferation of B cells and the development of T cells and mast cells. Important role in allergic responses.
- IL-5: role in differentiation of B cells, eosinophil production, and IgA production
- IL-6: secreted by macrophages, induces acute phase reaction
- IL-7: involved in B, T, and NK cell survival, development, and homeostasis
- IL-8: Neutrophil chemotaxis
- IL-9: stimulates mast cells
- IL-10: inhibits Th1 cytokine production
- IL-11: acute phase protein production
- IL-12: NK cell stimulation, Th1 cells induction
- IL-13: Stimulates growth and differentiation of B-Cells, inhibits Th1 cells and the production of macrophage inflammatory cytokines
- IL-14:
- IL-15: Induces production of Natural Killer Cells
- IL-16:
- IL-17: Induces production of inflammatory cytokines
- IL-18: Induces production of Interferon-Gamma (IFNy)
- IL-19:
- IL-20:
- IL-21:
- IL-22:
- IL-23: Increases angiogenesis but reduces CD8 T-cell infiltration
- IL-24:
- IL-25:
- IL-26:
- IL-27:
- IL-28:
- IL-29:
- IL-30:
- [| HGNC Gene Family Nomenclature: Interleu..."
Further Data On Term for interleukin
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Regularly Occuring Typos with interleukin include: niterleukin itnerleukin inetrleukin intreleukin intelreukin interelukin interluekin interlekuin interleuikn interleukni nterleukin iterleukin inerleukin intrleukin inteleukin intereukin interlukin interlekin interleuin interleukn interleuki unterleukin knterleukin onterleukin anterleukin enterleukin unterleukin ibterleukin ihterleukin ijterleukin imterleukin inrerleukin inferleukin ingerleukin inyerleukin intwrleukin intsrleukin intdrleukin intrrleukin intarleukin intirleukin intorleukin inturleukin inteeleukin intedleukin intefleukin intetleukin interkeukin interoeukin interpeukin interlwukin interlsukin interldukin interlrukin interlaukin interliukin interloukin interluukin interleykin interlejkin interleikin interleakin interleekin interleokin interleujin interleuiin interleulin interleumin interleucin interleukun interleukkn interleukon interleukan interleuken interleukun interleukib interleukih interleukij interleukim
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